Why Some People Can’t Absorb Vitamin D No Matter How Much They Take

You take your vitamin D… 

You get enough sunlight…

Your bloodwork says your levels are “fine.”

But you still feel tired, sluggish, and prone to getting sick.

What’s going on?

The truth is, not everyone can absorb vitamin D properly, no matter how much they take.

People assume vitamin D deficiency is just a lack of sun exposure or supplementation.

But for about 40% of people, the problem isn’t how much vitamin D they take…

It’s how their body processes it.

The Hidden Vitamin D Deficiency No One Talks About

Your body doesn’t just absorb vitamin D and use it instantly. 

First, it has to go through a conversion process—turning it into an active form your cells can recognize.

This is where the VDR (Vitamin D Receptor) gene comes in.

The VDR gene controls how well your body converts vitamin D into its active form. 

If you have a mutation in this gene, your body struggles to absorb and utilize vitamin D properly. 

This means you could have “normal” vitamin D levels on a blood test, but your cells aren’t actually using it.

Symptoms of deficiency (low energy, weak immunity, hormone imbalances) can persist even if you’re supplementing.

So, no matter how much vitamin D you take, your body still isn’t getting what it needs.

How the VDR Gene Affects Your Health

Vitamin D plays a major role in immune function, hormone production, and bone health.

When your body can’t process vitamin D properly, it creates a domino effect:

Immune dysfunction 

Vitamin D activates T-cells, the immune system’s defense against viruses and infections.

If your body can’t use vitamin D properly, your immune response weakens.

Low energy & mood swings 

Vitamin D regulates serotonin and dopamine, which affect mood and motivation.

A deficiency can leave you feeling fatigued or depressed.

Weakened bones & joint pain 

Your body needs vitamin D to absorb calcium.

Without it, bones become fragile, increasing the risk of fractures and osteoporosis.

Hormone imbalances 

Vitamin D plays a crucial role in testosterone and estrogen regulation.

Low levels can lead to fatigue, weight gain, and metabolic issues.

The Solution To The VDR Mutation

If your body struggles to absorb vitamin D, simply taking more won’t solve the problem. 

You need a smarter approach:

#1 - Switch to the right form of vitamin D 

Most supplements use vitamin D2, which is poorly absorbed.

Vitamin D3 (cholecalciferol) combined with K2 is far more effective.

#2 - Increase magnesium intake 

Magnesium helps convert vitamin D into its active form.

Without enough magnesium, your body can’t convert vitamin D properly.

#3 - Check your genetics 

Getting your genes tested can reveal if you’re one of the 40% who have a VDR gene mutation.

If it turns out you do, then you need to focus on activating it through the right form.

By correctly activating it, your body can still absorb and use vitamin D, even if you have this gene mutation.

This means prioritizing key nutrients like magnesium, and ensuring you get the right co-factors like vitamin K2 to direct calcium where it’s needed.

If you want to get your DNA tested, then book a call with my team.

You’ll be able to know if you have the VDR gene mutation, and which specific nutrients you need to optimize absorption.

Your body isn’t broken…

It just needs the proper tools to function at its best.

Until next time,

Kashif Khan

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease or prescribing any medication. If you have or suspect that you have a medical problem, promptly contact your regular healthcare provider.